名称:Recombinant Human C-C motif chemokine 4 protein(CCL4)

产品货号：AA10060

规格：20ug 100ug 1mg

产品详情

纯度：>96% as determined by SDS-PAGE and HPLC.

内毒素：Less than 1.0 EU/μg as determined by LAL method.

生物活性：Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 5.0-20 ng/ml.

基因名：CCL4

Uniprot No.：P13236

别名：MIP 1 beta; Secreted protein G 26; ACT 2; ACT-2; ACT2; AT744.1; AT744.2; C C motif chemokine 4; C C motif chemokine 4 like; C C motif chemokine ligand 4 like 1; C C motif chemokine ligand 4 like 2; CC chemokine ligand 4; CC chemokine ligand 4L1; CC chemokine ligand 4L1d2; CC chemokine ligand 4L2; CCL4; CCL4_HUMAN; ccl4l 1; CCL4L; CCL4L1; Chemokine (C C motif) ligand 4; Chemokine (C C motif) ligand 4 like 1; Chemokine (C C motif) ligand 4 like 1; telomeric; Chemokine (C C motif) ligand 4 like 2; Chemokine CC Motif Ligand 4; G 26; G 26 T lymphocyte secreted protein; G-26 T-lymphocyte-secreted protein; HC21; Immune activation 2; LAG 1; LAG-1; LAG1; Lymphocyte activation gene 1; Lymphocyte activation gene 1 protein; Macrophage inflammatory protein 1 beta; Macrophage inflammatory protein 1-beta; Macrophage inflammatory protein 1b2; MGC104418; MGC126025; MGC126026; MIP-1-beta; MIP-1-beta(1-69); MIP-1-beta(3-69); MIP1 beta; MIP1B; MIP1B1; Monocyte adherence induced protein 5 alpha; PAT 744; Protein H400; SCYA2; SCYA4; SCYA4L; SCYA4L1; SCYA4L2; SCYQ4L2; Secreted protein G 26; Secreted protein G26; SIS gamma; SIS-gamma; Small inducible cytokine A4 (homologous to mouse Mip 1b); Small inducible cytokine A4; small inducible cytokine A4-like; Small-inducible cytokine A4; T cell activation protein 2; T-cell activation protein 2

种属：Homo sapiens (Human)

蛋白长度：Full Length of Mature Protein

来源：E.Coli

分子量：7.8 kDa

表达区域：24-92aa

蛋白标签：Tag-Free

产品提供形式：Liquid or Lyophilized powder

功能：具有和趋化动力学特性的单细胞因子。与CCR5结合。CD8+ t细胞产生的主要hiv抑制因子之一。重组MIP-1-beta诱导不同株HIV-1、HIV-2和猿猴病毒(SIV)的剂量依赖性抑制。mip1 - β(3-69)的加工形式保留了诱导趋化因子受体CCR5表面表达下调的能力，并抑制CCR5介导的HIV-1进入t细胞。MIP-1-beta(3-69)也是CCR1和CCR2 B亚型的配体。

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